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CelticPoet 05-22-18 01:43 AM

Medication
 
I have severe depression and have tried several antidepressants. I can't abide the side effects. I have a stomach ulcer so cannot tolerate serotonin reuptake inhibitors. I have heart arrhythmias (PVCs) so cannot take medicines that work on norepinephrine. I have enlarged prostate so TCAs are not advisable. I have anxiety with depression so need a medicine that works on both. I don't need anything that agitates, sedates, or causes weight gain. I have tried moclobemide which didn't have a lot of side effects but didn't help, either. I took it for two weeks and it made me nervous and restless at the end. Tried Zoloft, caused stomach upset and headaches. Tried Cymbalta, caused bad insomnia. Tried Trintellix, caused trouble breathing and fatigue. Tried nortriptyline, caused increased heart rate and insomnia. Tried Wellbutrin, caused nervousness, and anxiety worsened. I've used Tianeptine; it helped but tolerance developed.

I've researched many antidepressants and seems there are none that I'm suited for. Can anyone help/make suggestions about antidepressants that might work for me? Thanks.

CelticPoet 05-22-18 04:02 AM

Can anyone help?

hottea654 05-30-18 10:40 PM

I'm not any real help with medicines. Sorry to hear you are having such trouble! My life's journey has lead me to eating an organic and mostly vegetable diet along with exercise to help with ailments. Vegetables are supposed to be the natural balancing, anti-inflammatory approach. I don't know if that is anything that will help you but so far it has worked the best out of the stuff I've been on or tried. Good luck with your journey! By the way, I recently read up on broccoli. It seems to do so many good things it might help out some of your physical issues.

RightFootRabbit 05-25-19 01:31 PM

Quote:

Originally Posted by CelticPoet (Post 2882873)
I have severe depression and have tried several antidepressants. I can't abide the side effects. I have a stomach ulcer so cannot tolerate serotonin reuptake inhibitors. I have heart arrhythmias (PVCs) so cannot take medicines that work on norepinephrine. I have enlarged prostate so TCAs are not advisable. I have anxiety with depression so need a medicine that works on both. I don't need anything that agitates, sedates, or causes weight gain. I have tried moclobemide which didn't have a lot of side effects but didn't help, either. I took it for two weeks and it made me nervous and restless at the end. Tried Zoloft, caused stomach upset and headaches. Tried Cymbalta, caused bad insomnia. Tried Trintellix, caused trouble breathing and fatigue. Tried nortriptyline, caused increased heart rate and insomnia. Tried Wellbutrin, caused nervousness, and anxiety worsened. I've used Tianeptine; it helped but tolerance developed.

I've researched many antidepressants and seems there are none that I'm suited for. Can anyone help/make suggestions about antidepressants that might work for me? Thanks.


Have you tried Remeron? Also goes by the name “Mirtazapine”? It’s a quadricyclic antidepressant, it’s a weird drug, I’ve also tried Ssris Snris and various others with no result in the past, but this one seems to help, it’s biggest side effect is increased appetite but I only noticed a very small change in appetite for a few days at the start and when increasing the medication.


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