I've tried Wellbutrin 3 times between 1 and 3 weeks with around a 50 mg dosage which is very small but it always seems to irritated my prostate. So now after taking it for 5 days my prostate is irritated again and tomorrow I will go in for a prostate Biopsy and of course I won't be taking Wellbutrin again. Has anyone else experience this from Wellbutrin?

i did notice that wellbutrin makes me swear like a sailor! I mentioned it to a psychiatrist 10 years ago and he switched me to something else. but the wellbutrin was working, just i was cussing a lot. so after some time on weird meds that messed up my physical health badly, i went to my primary doc and said put me back on wellbutrin cause it worked and everyone will jut have to deal with my cursing. so, yeah meds do different things to different people. you can go to the FDA site or the wellbutrin site and leave feedback, maybe there are others. I did that for some of the harsher meds and found out enough stuff about them that i will never take them again. hope you find a med that will give you relief and not screw up your physical health. good luck, it's all trial and error till you find the right combination.