So I've been on Pristiq for over 2 years. I have put on about 10kg in the last 2 years but only just realised it all really started around the same time that I started on Pristiq. I was on cymbalta for a couple of years before that and didn't put on any weight. And I've been on other stuff before that and had no weight gain either.

I went to a new Dr the other day and she told me that after 6 months the Dr should have lowered my dose down to 50mg because the side effects get too bad on the 100mg. Now I'm hoping that lowering the dose can help with my weight loss but am wondering if anyone has had any similar issues and / or success stories?

Pretty fucked up when the thing that you are taking for depression makes you even more depressed in the end. I'm used to being petite, but the last 2 years have been so hard with my weight. I hate it. I don't feel like myself. I don't look like myself.

Mabey you can try another type.. Prob best to speak to the GP. I was on pristiqe, yes I put on weight and had the worst head buzzes. It drove me crazy.
I'm on cymbalta 60mg now. And I feel better,
Aropax is another one that I found good,

Some meds I've been on have made me gain weight and the idiot doctor I had even noticed but didn't switch me. I hope this doesn't happen to you but i've put 3 months of solid exercise into losing weight and only lost 3 lbs. Another thing they should be doing is checking your blood for any change in your thyroid and a couple of other things as well for side effects. Be vigilant look up the med side effects ask the pharmacist for a list of side effects and look on the internet as well.

I was also on Pristiq for 3 years, and gained weight.