Yah, I looked it up to find out more about what it does when you abuse the drug. It looks like it makes you have pelvic pain and increased urgency to urinate. Abusing the drug causes general lower urinary tract dysfunction. There is plenty of information on the net about what it does in a negative way for people using the drug as frequent recreational drug use.
So far, I've found other articles that talk about the drug or parts of the drug helping the treatment of depression and it does sound hopeful that we will see something relatively soon. The following is an excerpt from a larger article that talks about the development of Ketamine into a depression treatment option:
"....Manji is embracing ketamine as lead that will help develop other drugs, the first of which could be available by 2017. Four of the NIH scientists who have worked on ketamine in depression have followed him to Johnson&Johnson. The first of these medicines, esketamine, is an isomer of ketamine; like many drugs, ketamine molecules come in two forms with the exact same molecular formula but different arrangements of atoms. By separating out the more effective one, J&J is lowering the ketamine dose. More importantly, esketamine is given not through an intravenous line directly into the blood, as ketamine is, but as a nose spray. Manji says that he believes doctors and patients will be far more likely to use an intranasal drug than an IV. The dose being used is only a fraction of that for anesthesia
Esketamine will be used only in clinics, and not given to individual patients. J&J is working on a plan to prevent it from being abused as it develops the drug. It already has fast-track status from the Food and Drug Administration, and Manji says he hopes to apply for the new “breakthrough” designation offered by the agency as well. A 30-patient european clinical trial of the new drug is set to finish in 2013. It’s not yet clear whether esketamine will be used only to get people out of a depressed and potentially suicidal state, or whether it could become a chronic treatment, given at the doctor’s office every two days.
But that’s just the beginning, Manji says. The understanding of brain receptors that is emerging from this work could result in other new drugs......"
Forbes| PHARMA & HEALTHCARE | 5/23/2013 @ 1:33PM |
Johnson & Johnson Is Reinventing The Party Drug Ketamine To Treat Depression
We have to become creative problem solvers, not just tolerant burden barers.
Last edited by hottea654; 07-23-13 at 02:15 AM.