Ketamine to rebuild synapses and treat depression
Take This Life  

Go Back   Take This Life > Treatment and Resources > Resources > Depression News

Ketamine to rebuild synapses and treat depression

This is a discussion on Ketamine to rebuild synapses and treat depression within the Depression News forums, part of the Resources category; Have any of you all read this article yet? From the sounds of it, we should all go get prescribed ...

join us
Reply
 
LinkBack Thread Tools
Old 07-21-13, 12:24 AM   #1
Senior Member
 
hottea654's Avatar
 
Join Date: Apr 2009
Location: Texas
Posts: 3,412
My Mood:
Default Ketamine to rebuild synapses and treat depression

Have any of you all read this article yet? From the sounds of it, we should all go get prescribed some Ketamine in the pursuit of a better, happier life. I'm sure there is more to it then this article outlines, but it does sound promising!


YaleNews | Yale scientists explain how ketamine vanquishes depression within hours
__________________
We have to become creative problem solvers, not just tolerant burden barers.
hottea654 is offline   Reply With Quote
Old 07-22-13, 06:43 PM   #2
TTL Bronze Member
 
mmch85's Avatar
 
Join Date: Nov 2010
Location: LaanDaan
Posts: 5,709
My Mood:
Default

ive taken a lot of ket... illegally of course

Yep. wonder drug, puts a silver lining on life. Though at the cost of having your bladder removed, rots it out very fast.
__________________
I hate that early bird........ You know the one who catches the worm.........get back in ya nest ya feathery little mug.........
mmch85 is offline   Reply With Quote
Old 07-23-13, 01:12 AM   #3
Senior Member
 
hottea654's Avatar
 
Join Date: Apr 2009
Location: Texas
Posts: 3,412
My Mood:
Default

Yah, I looked it up to find out more about what it does when you abuse the drug. It looks like it makes you have pelvic pain and increased urgency to urinate. Abusing the drug causes general lower urinary tract dysfunction. There is plenty of information on the net about what it does in a negative way for people using the drug as frequent recreational drug use.

So far, I've found other articles that talk about the drug or parts of the drug helping the treatment of depression and it does sound hopeful that we will see something relatively soon. The following is an excerpt from a larger article that talks about the development of Ketamine into a depression treatment option:

"....Manji is embracing ketamine as lead that will help develop other drugs, the first of which could be available by 2017. Four of the NIH scientists who have worked on ketamine in depression have followed him to Johnson&Johnson. The first of these medicines, esketamine, is an isomer of ketamine; like many drugs, ketamine molecules come in two forms with the exact same molecular formula but different arrangements of atoms. By separating out the more effective one, J&J is lowering the ketamine dose. More importantly, esketamine is given not through an intravenous line directly into the blood, as ketamine is, but as a nose spray. Manji says that he believes doctors and patients will be far more likely to use an intranasal drug than an IV. The dose being used is only a fraction of that for anesthesia
Esketamine will be used only in clinics, and not given to individual patients. J&J is working on a plan to prevent it from being abused as it develops the drug. It already has fast-track status from the Food and Drug Administration, and Manji says he hopes to apply for the new “breakthrough” designation offered by the agency as well. A 30-patient european clinical trial of the new drug is set to finish in 2013. It’s not yet clear whether esketamine will be used only to get people out of a depressed and potentially suicidal state, or whether it could become a chronic treatment, given at the doctor’s office every two days.
But that’s just the beginning, Manji says. The understanding of brain receptors that is emerging from this work could result in other new drugs......"

Forbes| PHARMA & HEALTHCARE | 5/23/2013 @ 1:33PM |
Johnson & Johnson Is Reinventing The Party Drug Ketamine To Treat Depression
__________________
We have to become creative problem solvers, not just tolerant burden barers.

Last edited by hottea654; 07-23-13 at 01:15 AM.
hottea654 is offline   Reply With Quote
Old 07-29-13, 05:56 AM   #4
TTL Bronze Member
 
mmch85's Avatar
 
Join Date: Nov 2010
Location: LaanDaan
Posts: 5,709
My Mood:
Default

im sure it does help with depression somewhat. But i couldn't imagine using it on a daily basis. Even the tiniest amount can make your limbs feel disconnected from your brain and then you have to think "lift left leg up, move left leg forward, put left leg down, lift right leg..... etc. needless to say it makes simple tasks very very hard....
It is after all a tranquilliser
__________________
I hate that early bird........ You know the one who catches the worm.........get back in ya nest ya feathery little mug.........

Last edited by Forest; 08-06-13 at 06:05 PM.
mmch85 is offline   Reply With Quote
Old 07-29-13, 07:11 PM   #5
Senior Member
 
hottea654's Avatar
 
Join Date: Apr 2009
Location: Texas
Posts: 3,412
My Mood:
Default

I guess we'll just have to see what kind of thing they come out with. It sounded like a very tiny amount from the specifics I found. I think the new possibility of help for people is great but I can see how you have some doubts after your experiences. Time will tell, I imagine.
__________________
We have to become creative problem solvers, not just tolerant burden barers.

Last edited by Forest; 08-06-13 at 04:02 PM.
hottea654 is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On



All times are GMT -5. The time now is 10:03 AM.


Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Shoutbox provided by vBShout v6.2.1 (Lite) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.
 

Content Relevant URLs by vBSEO 3.3.2