This herb is a potent antidepressant when taken consistently for several weeks to months. The effects seem to be cumulative, and take a while to begin. Generally, one will notice an elevation of mood, an alleviation of the preoccupation with suicide if one is suicidal, and an increased interest in life.
The herb is best taken fresh, in tincture form. You can purchase tinctures at your local herb or health-food store. If you cannot take an alcoholic tincture, or if you prefer to be more actively involved in your medicine making, you can use dried Hypericum to make a sun tea. This is an extremely effective method of preparation. To make a standard sun tea, simply immerse the dried herb in boiling water in a glass container, cover, place out in the sun for 24 hours. Use approximately one ounce of herb to one half gallon of water. Take one 8 ounce cup of this medicine 3x daily for four to six weeks, at least. The sun potentiates the effects of the herb as an antidepressant.
Interestingly, St. John's is also beneficial for all kinds of nerve damage, including physical nerve damage caused by traumatic injury or surgery. It heals the structural aspects of the nervous system.
Almost all clinical trials involving Hypericum involve a pill form of the medicine found in the plant. In my opinion, these pills are not as effective as the real thing, the whole, unadulterated plant.
There is some question as to whether or not Hypericum should be used by people who have bipolar disorder. The question lies in the possibility that Hypericum may initiate a manic episode. This has not been proven.
However, if you are bipolar, approach this plant with some caution.
Hypericum should not be used by individuals who are taking immunosuppressant medication following an organ transplant.
Good luck with your endeavors! This plant helped me to not commit suicide in the past, and I highly recommend it!